In vitro and in vivo safety evaluation of Dipteryx alata Vogel extract

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In vitro and in vivo safety evaluation of Dipteryx alata Vogel extract

BACKGROUND Dipteryx alata Vogel popularly known as "baru" is an important commercial leguminous tree species from the Brazilian Cerrado, which possess medicinal properties, besides its fruits consumption by animals and humans. The use of the "naturally occurring plants" as herbal remedies and foods mainly from leaves, seeds, flowers and roots of plants or extracts require precautions before ens...

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In vitro antiophidian properties of Dipteryx alata Vogel bark extracts.

Extracts from Dipteryx alata bark obtained with different solvents (hexane, dichloromethane, ethyl acetate and methanol) were mixed in vitro with Bothrops jararacussu (Bjssu, 40 μg/mL) and Crotalus durissus terrificus (Cdt, 15 μg/mL) snake venoms, and applied to a mouse phrenic nerve-diaphragm preparation to evaluate the possible neutralization of venom effects. Cdt venom neurotoxic effect was ...

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Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom.

The effect of four sub-extracts prepared from the lyophilized hydroalcoholic bark of Dipteryx alata (Leguminosae-Papilionoideae) dissolved in a methanol-water (80:20) mixture through a liquid-liquid partition procedure has been investigated against the neuromuscular blockade of the venom of the snake Bothrops jararacussu. The active CH₂Cl₂ sub-extract has been extensively analyzed for its chemi...

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Optimizing sampling efforts for ex situ conservation of genetic variability of Dipteryx alata Vogel

Background The “Baru” tree (Dipteryx alata Vogel) is an endemic species from the Cerrado biome, but widely distributed within the biome and abundant in several of its habitats [1].The species is also important in commercial terms for recover of degraded areas, and seeds are consumed in natura and are source of raw material for small and middle-sized food industries [2].Thus, a more detailed kno...

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Combining multiple models to predict the geographical distribution of the Baru tree (Dipteryx alata Vogel) in the Brazilian Cerrado.

The Brazilian Cerrado is a biome of great biodiversity, but detailed information about the diversity and distribution of species in this region is still insufficient for both testing ecological hypotheses and for conservation purposes. Among native plants in the Cerrado, Dipteryx alata Vogel (commonly known as the "Baru" tree), has a high potential for exploitation. The aims of this paper were ...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2012

ISSN: 1472-6882

DOI: 10.1186/1472-6882-12-9